tert-butyl 4-(methylamino)piperidine-1-carboxylate

tert-butyl 4-(methylamino)piperidine-1-carboxylate - Names and Identifiers

Name	1-Boc-4-Methylaminopiperidine
Synonyms	N-BOC-4-METHYLAMINOPIERIDINE N-Boc-4-Methylaminopieridine 1-Boc-4-Methylaminopiperidine N-Boc-4-Methylaminopiperidine N-BOC-4-METHYLAMINOPIPERIDINE N-Boc-4-N-Methylamino Piperidine N-BOC-4-N-METHYLAMINO PIPERIDINE 4-N-METHYLAMINO-1-BOC-PIPERIDINE 4-N-Methylamino-1-Boc-Piperidine 1-N-Boc-4-(Methylamino)Piperidine 1-N-BOC-4-(METHYLAMINO)PIPERIDINE Tert-Butyl 4-(Methylamino)Piperidine-1-Carboxylate tert-butyl 4-(methylamino)piperidine-1-carboxylate 4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS	147539-41-1
InChI	InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-7-5-9(12-4)6-8-13/h9,12H,5-8H2,1-4H3

tert-butyl 4-(methylamino)piperidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C11H22N2O2
Molar Mass	214.3
Density	1.005 g/mL at 25 °C
Boling Point	289.0±33.0 °C(Predicted)
Flash Point	>110℃
Vapor Presure	0.002mmHg at 25°C
Appearance	Transparent liquid
Color	Colorless to Almost colorless
pKa	10.19±0.20(Predicted)
Storage Condition	2-8°C
Sensitive	`sensitive` to heat and air
Refractive Index	n20/D1.468
MDL	MFCD02259411
Physical and Chemical Properties	WGK Germany:3

tert-butyl 4-(methylamino)piperidine-1-carboxylate - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	2810
WGK Germany	3
FLUKA BRAND F CODES	10-34
HS Code	29339900
Hazard Class	6.1
Packing Group	Ⅲ

tert-butyl 4-(methylamino)piperidine-1-carboxylate - Introduction

It is an organic compound with the chemical formula C14H24N2O2.

Its properties are as follows:
-Appearance: White crystalline solid
-Melting Point: about 210-215 ° C
-Solubility: Soluble in polar organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane

The purpose of:
-It is an important organic synthesis intermediate and is widely used in the field of pharmaceutical synthesis.
-It can be used to synthesize a variety of hydrogenated pyridine compounds and other nitrogen-containing organic molecules.

Preparation Method:
It is usually synthesized through the following steps:
1. 1-bromo-4-methylpiperidine is reacted with tert-butoxycarbonyl isocyanate in the presence of a base.
2. The resulting intermediate will be purified by acid treatment and crystallization to obtain the target product.

AI Safety information:
-Pay attention to personal protection during operation, wear appropriate gloves, safety glasses and masks.
-Avoid inhaling dust or contact with skin and eyes.
-Maintain good ventilation during handling.
-Follow the relevant safety procedures and store in a sealed container, away from heat and fire sources.

Last Update：2024-04-09 19:05:46